Progesterone and Endocannabinoid Interaction Alters Sperm Activation
نویسندگان
چکیده
منابع مشابه
WORLD OF REPRODUCTIVE BIOLOGY: Progesterone and Endocannabinoid Interaction Alters Sperm Activation
A recent study in Science finds that α/β-hydrolase domain-containing protein 2 (ABHD2) is a novel nongenomic progesterone receptor that holds the CatSper cation channel open while progesterone elevates sperm cytoplasmic calcium ion (Ca) levels and triggers sperm hyperactive motility. ABHD2 functions as a lipid hydrolase, breaking down arachidonoylglycerols (2-AG/1AG)—endocannabinoid components ...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2016
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.116.142554